Sunday, May 11, 2008

SURGERY March 2008

COURTESY: DR: ALTAF GHUMRO &
PREPARED BY DR: MUHAMMAD SHEERAZ AKHTAR SOOMRO


1] A newborn child has abdominal swelling on the right side of the umbilical cord. It is not covered with amnion. The condition is

A} Gastroschisis
B} omphalocele

2] Which of the following is not related to Meckel’s Diverticulum?

A} is remnant of urachas
B} lies 60 cm proximal to illeocecal Valve

3] A boy is excreting meconium from rectum and has severe constipation. The rectal examination showed no ganglion cells. The condition is called

A} Intussusceptions
B} Hirschsprung’s disease

4] Regarding somites

A} They develop on both sides of notochord.
B} they develop from lateral plate mesoderm

5] Regarding diaphragmatic hernia the most likely is

A} Absence of septum transversum
B} Failure of pluiroperitoneal membrane

6] Which one of the following is not the derivative of 1st (mandible) pharyngeal arch?
A} Incus
B} Malleus
C} Stapes
D}
E}

7] Embrologically, Which one of the following is not the developmental remant

A} lateral umbilical ligament
B} Medial umbilical ligament
C} Median umbilical ligament
D} ligamentum teres
E} ligamentum venosum

8] The part of mouth derived from ectoderm is

A} Epithelium of parotid salivary gland
B} Epithelium of Tongue
C} Floor f mouth
D}
E}

9] A male with Gynaecomastia, small testes, diagnosed as Klienfelters syndrome. The karyotype involved is

A} 45 XO
B} 46 XX
C} 47 XXX
D} 47 XXy
E} 47 XX

10] Somites are derived from

A} Intermediate mesoderm
B} Paraxial mesoderm
C} Lateral plate mesoderm
D} Ectoderm
E} Endoderm

11] An I/V Urograph of 8 year old boy shows Excretion of dye normal I kidney but absence of shadow on left side. Instead there is a small shadow just above the bladder on the left side. Which one of the following is most likely?

A} Horse shoe kidney
B} Constricted ectopic kidney
C} Pelvis kidney
D} Non rotating kidney
E} Unilateral renal agenesis

12] Which one of the following is not formed from urogenital sinus?

A} Bartholin’s gland
B} Urethral glands
C} Para urethral glands
D} Seminal vesicle
E}

13] Virus damage the cell by

A} making the pores in cell membrane
B} Forming free radicals
C} Altering the formation of proteins
D} Nuclear damage
E} using energy for their own metabolism

14] The tissue damage by Ionization Radiation is due to
A) Damage to Golgi bodies
B} Formation of free radicals
C} Hydropic degeneration
D} Metaphase of cell
E} Swelling of cells
15] All are features of IRREVERSIBLE cell injury EXCEPT
A} Karyolysis
B} Karyorhexis
C} Autolysis
D} Shrinkage of mitochondria
E} Appearance of myelin figure
16] Which one of the following is least likely involved in increasing Osteoporosis

A} Increased wt: on bone
B} Renal cell carcinoma
C} Carcinoma prostate
D}
E}

17] Patient X-Ray shows hilar lymph nodes. Granuloma but no necrosis. What is the diagnosis?

A} Sarcoidosis
B} Silicosis
C} Tuberculosis
D}
E}

18] In women the most common form of necrosis after trauma is due to

A} Trauma to fatty tissue
B}
C}
D}
E}

19] Dystrophic calcification is present in which of the following

A} Acute pancreatitis
B} Malaria
C} Tuberculosis
D}
E}

20] Which one of the following is most likely feature of reversible injury?

A} Cell swelling
B} Karyorhexis
C} Decreased glycogen
D} Myelin figures
E}

21] A person fell on road and got an abrasion on elbow the first event likely occur would be

A} Vasoconstriction
B} Platelet adhesion
C} Platelet aggregation
D}
E}

22] Which one of the following facilitates phagocytosis in neutrophils?

A} C5a
B} C3a
C} C3b
D} C3 - C5 complex
E}

23] Which one of the following is potent antioxidant?

A} Vitamin A
B} Vitamin C
C} Vitamin E
D} Transferrin
E}

24] Which one of the following among Arachidonic acid metabolite is most likely function mediated in phagocytosis?

A} Chemo taxis
B} Diapedisis
C} Transmigration
D}
E}

25] Which one of the following is potent COX-II INHIBITOR?

A} Aspirin
B} Celocoxib
C} Indomethacin
D} Meloxicam
E} Piroxicam
26] In case of pulmonary embolism extensive infarction causes sudden death due to

A} Air embolism
B} Fat embolism
C} Thromboembolism
D}
E}

27] A patient was operated for abdominal surgery. A few days after he developed pain and swelling in his right leg. Which one of the following is most likely?

A} endothelial injury
B} hypercoagubility
C} stasis and endothelial injury
D}
E}

28] A soldier has profuse bleeding. He was admitted in the hospital. Which one of the following should be given immediately?

Fresh frozen plasma
B} 20 days old blood
C} 3 days old blood
D}
E}

29] A boy was born with the condition of polycystic kidney disease. Which one of the following is correct?

A} Autosomal Dominant disorder
B} Autosomal recessive disorder
C} X- linked disorder
D}
E}

30] In a renal transplantation, which one of the following is single most significant test to be done?

A} ABO blood grouping of donor and recipient
B} HLA typing and matching
C} Donor and recipient should be close relatives
D}
E}

31] A organ was transplanted to the patient, but within 10 mins the organ failed. Which one of the following is likely etiology?

A} Antibody mediated
B} T-Cell mediated
C} Preformed antibodies
D}
E}

32] AIDS occur in the presence of

A} Kaposi’s sarcoma
B}
C}
D}
E}

33] A 2 year old boy is suspected as HIV positive, which one of the following is the confirmatory test in the boy

A} ELISA test
B} Western Blot test
C} PCR
D} Increased levels of HIV in T lymphocytes
E}

34] A 10 year old boy was operated for gastrectomy, which one of the following type of anemia is developed postoperatively

A} Megaloblastic anemia
B} Iron deficiency anemia
C} Normocytic norm chromic anemia
D}
E}

35] Autoimmunity is not involved in which one of the following

A} Pernicious anemia
B} Grave’s disease
C} Diabetes mellitus
D} Hashimoto’s thyroiditis
E} Thymoma

36] In case of hashimoto’s thyroiditis, which one of the following is seen?

A} Anti thyroglobulin
B}
C}
D}
E}

37] To differentiate Chron’s disease from Ulcerative colitis, which one of the following is likely significant regarding Chron’s disease

A} has increased frequency to cancer
B} Involves both small and large intestine
C}
D}
E}

38] Regarding alcoholic hepatitis, following is finding

A} Mallory bodies
B}
C}
D}
E}

39] A 20 year old girl has developed Galactorrhea due to prolactinoma. Bromocriptine is given to treat it the drug causes

A} Inhibition of prolaction from pituitary gland
B} Decreased prolaction from hypothalamus
C} Inhibition of prolaction from breast
D} Stimulation of prolaction of anterior pituitary
E}

40] An unconscious patient presented in ED does not respond to Naloxone. Which of the following drug has been taken by this patient?

A} Morphine
B} Heroine
C} Pethidine
D} Phenobarbital
E}

41] Strongest layer of small intestine is

A} Mucosa
B} Sub mucosa
C} Circular layer
D} Serosa
E} Longitudinal layer

42] Regarding adrenal medulla which one of the following is true?

A} Secretes epinephrine and Norepinepinephrine in 80/20 ratio
B}
C}
D}
E}

43] R.E.R most likely

A} Synthesizes protein
B} Synthesizes lipids
C}
D}
E}

44] Half life of insulin is

A} 5 mins
B} 90 mins
C} 120 mins
D}
E}

45] Insulin

A} Converts glycogen to glucose
B} Stimulates protein synthesis
C} Stimulates lipolysis
D}
E}

46] Which one of the following most likely contains abundant cholesterol?

A} VLDL
B} LDL
C} Chylmicrons
D} HDL
E}


47] Which one of the following most likely causes Increase in GFR?

A} Constriction of afferent arteriole
B} Constriction Of efferent arteriole
C}
D}
E}

48] Gastric emptying is delayed by

A} Gastrin
B} Secretin
C} CCK
D}
E}

49] Which one of the following pancreatic enzyme is most likely involved in fat absorption

A} Amylase
B} Lipase
C}
D}
E}

50] Smooth muscle

A} Contain sarcomere
B} T-tubules are present
C} Gap junctions are present
D} Forms motor end plate
E}

51] Steady pressure on skin is perceived by

A} Pacinian’s corpuscle
B} Ruffini’s corpuscle
C} Meissener’s Corpuscle
D} Golgi tendon organs
E}

52] Which one of the following is related to pain?

A} Serotonin
B} Substance P
C}
D}
E}

53] Free nerve endings have receptor for

A} Light touch
B} Pressure
C} Pain
D} Vibration
E}

54] Which one of the following has highest pressure?

A} Pulmonary artery
B} Left atrium
C} Right atrium
D} SVC
E}

55] Flow of current through junctions in the muscle

A} Smooth muscle
B} Skeletal muscle
C} Cardiac muscle
D}
E}

56] A profusely bleeding patient develops hypotension, which one of the following would be immediate mechanism to maintain B.P

A} Baroreceptor reflex
B} Chemoreceptor reflex
C} Secretion of ADH
D} Aldosterone
E} Renin angiotensin mechanism

57] Water enters into the cell by

A} Pinocytosis
B} through pores
C} Simple diffusion
D} Facilitated diffusion
E} Active transport

58] Insulin secretion is controlled by

A} Glucagon
B} increased glucose
C} Decreased glucose
D}
E}

59] Systolic B.P is highest in

A} Pulmonary arteries
B} Cerebral arteries
C} Renal arteries
D} Brachial arteries
E}

60] End diastolic volume depends on

A} Atrial contraction
B} Distensibility of ventricles
C} Duration of diastole
D} Venous return
E}

61] Mean electrical axis of heart is deviated to left if

A} Heart is angulated on right side
B} Pulmonary stenosis
C} Right bundle branch block
D} COPD
E}

62] Pulse Oxymeter measurement gives error in the reading if

A} Pt. is dark skin
B} Increased conc: of Hb A
C} Increased Conc: of Hb F
D} Aortic stenosis
E}

63] Secretion of potassium by distal collecting tubule decrease by

A} Increase in potassium in diet
B} Hyperaldosteronism
C} Metabolic alkalosis
D} Spironalactone intake
E} Thiazide diuretic



64] Absorption of iron is markedly affected by

A} Ingestion with meal
B} Partial gastrectomy
C} Trivalent form
D}
E}

65] Patient with pancreatitis has developed steatorrhea due to deficiency of

A} Lipase
B} Pepsin
C} Amylase
D} Renin
E}

66] Absorptive surface of small intestine is

A} 50
B} 100
C} 200
D} 350
E} 500

67] Daily dietary protein for 70 kg. Man is

A} 12 gm
B} 120gm
C} 200 gm
D} 150 gm
E}

68] Source for metabolic fuel for liver in post absorptive state is

A} Glucose
B} Ketones
C} Glycerol
D} Fatty acids
E}

Saturday, May 10, 2008

ANESTHESIA MARCH' 08

FCPS I - 26th MARCH' 08
ANESTHESIA

1. If a drug is taken orally. How will u assess the drug?
a. plasma drug conc
b. blood drug conc
c. urine drug conc

2. Regarding Nitroglycerine, all are true except
a. extensive 1st pass effect
b. venodilator
c. dec venous return
d. dec HR
e. t1/2 is 3-5 min

3. Warfarin, effect inc by
a. Cimetidine

4. Why the dose of theophylline in infant is smaller than in adults
a. dec metabolism
b. dec plasma protein binding

5. Enzyme induction occurs in:
a. liver
b. kidney
c. heart
d. adrenals

6. Digoxin toxicity
a. Inc K*
b. Inc Mg*
c. dec Ca**
d. dec Na*
e. alkalosis

7. Secondary active transport occurs thru
a. glucose
b. Na*
c. K*
d. Urea

8. 2 liters of 2 different gases of diff mol wt contain
a. equal no. of molecules
b. equal no. of atoms

9. Capillary permeability is inc by
a. hypertension
b. plasma colloid osmotic pressure
c. intersitial hydrostatic press
d. altered permeability

10. PG in inflammation dec by:
a. aspirin
b. corticosteroids
c. phosphodiesterase inhibitors

11. Which is true.
a. all parasymp are cholinergic
b. all sympathetic are adrenergic
c. all post-gang parasymp are cholinergic

12. Gastric motility is inc by:
a. inc gastrin
b. ACh
c. Secterin
d. Somatostatin

13. Gastric acid is inc by
a. Gastrin
b. ACh
c. Secterin
d. Somatostatin

14. Basal level of bile

15. alpha recptors effects ?
a. inc HR
b. lipogenesis
c. midriasis
d. piloerector contraction
e. bronchodilator

16. Beta effect ?
a. Inc HR and force of contraction

17. ACh effect?
a. Inc salivation
b. inc sweating
c. constipation

18. Thirst is dec by:
a. ADH
b. aldosterone
c. Ag II
d. baroreceptor efferent
e. inc Hematocrit

19. promotes each others actions
a. atropine and reserpine
b. amytriptyline and reserpine
c. atropine and amitryptyline

20. After induction of anesthesia by 10 mg/kg thiopentone, pt is hypotonic. Cause ?
a. hypersensitivity
b. dec HR
c. dec contractility

21.In hypertonic obs cardiomyopathy, which Ca** channel blocker is used:
a. Nifedipine
b. Nicardipine

22. Loop diuretics + thiazides enhance each others effect ( Dec NaCl abs) at:
a. descending loop of Henle
b. ascending loop of Henle
c. proximal convoluted tubule
d. distal convoluted tubule
e. collecting duct

23. Pt with mild CCF. Treatment started. 1 week later pt complains of severe pain at Rt big toe. Cause:
a. thiazide
b. furosemide
c. ACEi
d. amiodarone

24. Metastatic pleural effusion. Drug to be given:
a. streptomycin
b. clindamycin
c. corticosteroids
d. bleomycin

25. Monotherapy for mild CCF:
a. digoxin
b. captopril
c. nifedipine
d. propranolol

26.Pacemaker for complete heart block. Terminals shd be in:
a. SA node
b. AV node
c. Rt atrium
d. purkinje
e. Rt ventricle ..............(correct)

27. Infant with renal abnormality (renal artery stenosis). Drug responsible:
a. ACEi
b. Ca** channel blocker
c. amiodarone

28.Lungs inactivate Bradykinin by:
a. enz involved in converting kallikrein to plasma protein

29.After loss of 1 litre of blood in 5 min:
a. diastolic press dec
b. systolic press dec
c. aldosterone inc
d. no change

30. CO = VR. Large hump on left of cardiac pacing mentions:
a. inc contractility
b. inc HR
c. inc end-diastolic vol

31. Amiodarone.........> MOA

32. Lidocaine. MOA?
a. dec abnormal tissue conduction and no effect on normal tissue
b. inc PR interval
c. dec atrial contraction
d. dec AV conduction
e. inc QRS
f. inc QT

33. Class IA antiarrythmic drugs
a. Lidocaine
b. quinidine
c. procainide
d. amiodarone

34. Lidocaine as antiarrrythmic:
a. blocks Na* channels
b. Beta blocker
c. K* channel blocker

35.Verapamil ..... as antiarrythmic ?

36.Drug that inc extracellular K* (moves K* out of the cell):
a. Angiotensin
b. H2CO3
c. Carbonic anhydrase
d. pH
e. exercise

37. Sec K* in renal cells
a. metabolic alkalosis
b. carbonic anhydrase

38. Consistent finding in hypoKalemia
a. prolong vomiting
b. diarrhea
c. ureters attached to colon

39. Metabolic alkalosis
a. renal failure

40. ARF- most effect.
a. PCT
b. DCT
c. LOH
d. CD

41. Hb 8.0, HCO3- inc (35), pH Inc, Ca++ dec. Cause
a. ARF
b. Vit D def
c. folic acid deficiency
d. PTH

42. Anesthetics differ from anelgesics in:
a. only alter A delta and C fibers
b. Anesthetics effect at cerebral level and analgesics at spinal cord level
c. affects only pain and temp and no other sensory modalities

43. High output cardiac failure
a. Thiamine
b. B2
c. B6
d. Folic acid

44. 90 yrs old lady with purplish large patch on Rt hand and arm. No itching or pain. No comorbids, Otherwise Normal. Reason?
a. Capillary abn
b. Prothrombin
c. Vit K dependent clotting factors

45. 10 yrs old girl from Baluchistan c/o fatiguw, lethargy, mild jaundice, discoloration of skin, enlarged spleen. Hb 8.0, MCV 58, S. Ferritin 1000. Appropriate treatment?
a. deferroxamine
b. blood transfusion
c. iron transfusion

46. Death d/t embolism after accident
a. Fat
b. tumor cells
c. air
d. thromboembolism

47. Warfarin, effects on:
a. Factor VIII
b. factor III
c. Prothrombin

48. Ibpratopium bromide given by nebulization:
a. dec ACh release in bronchi
b. vasodil
c. inc secretion

49. Mast cell stabilizer.
a. Na chromoglycate

50. T1/2 of desmethyl diazepam, an inactive metabolite of diazepam is:
a. 20-50 hrs
b. 50-100 hrs
c. 100-200 hrs
d. 36-200 hrs ................... (correct)

51. Post menopausal women with brease ca. DOC
a. Tamoxifen

52. Sec released from thyroid gland entering circulation is:
a. Thyroxine
b. Free T3
c. free T4
d. TSH
e. TRH

53. Cushing's triad:
a. Inc ICP, HTN, Bradycardia
b. Inc ICP, hypoTN, bradycardia
c. inc ICP, hypoTN, tachycardia
d. inc ICP, HTN. tachycardia
e. dec ICP, HTN, tachycardia

54. CSF
a. total 150 ml
b. production rate 20 ml/hr
c. produced by ependymal cells of choroid plexus
d. drained by lymphatics

55. CSF:
a. Inc K* than plasma
b. dec glucose
c. dec specific gravity

56. PTH
a. inc PO4 abs from renal tubules
b. inc Ca resorption from bones
c. CRF
d. Anemia

57. Imp buffer in interstitial fluid
a. H2CO3
b. Hb
c. plasma pr.
d. PO4

58. Cell wall synthesis inhib
a. Penicillin

59. Sulphonamides inhibit
a. tetrahydrofolate in bacteria

60. Dark urine after starting ATT.
a. Rifampin

61. 1 week after starting of ATT, pt c/o pain in big toe. Reason
a. INH
b. Rifampin
c. Ethambutol
d. PZA

62. Needle inserted at paramedian vertebral canal pierces:
a. ant spinal lig
b. post spinal lig
c. supraspinal lig
d. interspinal log
e. ligamentum flavum

63. Pseudomembrane colitis linked to:
a. clindamycin
b. penicillin
c. cephalosporins
d. erythromycin

64. Regarding chemotherapy all are true, except:
a. often multi therapy is not curative
b. req daily dosing of multiple drugs for long time

65. Flumazenil
a. onset of action 30-60 min
b. all unconscious pts must be screened by this drug
c. paradoxical tachycardia
d. max safe dose 1 mg/day

66. Isoflurane
a. MAC 1.9
b. req special vaporizer
c. dec HR

66. Sevoflurane
a. dec HR
b. req use of normal vaporizer

67. MAC of Sevoflurane with 60% NO
a. 0.66-0.68

67. Ether causes
a. autonomic stimulation

68. Enflurane
a. EEG typical of seizures
b. not concerned to dose / conc adm
c. inc ICP
d. nonevident facial spasm

69. More pungent.
a. Isoflurane
b. enflurane
c. desflurane at MAC <1

70. Halothane

71. Metabolism of halides to release fluroide levels in descending order:
a. desfurane < isoflurane < enflurane < sevoflurane < halothane < methoxyflurane
0.02 0.2 2.5 3 - 5 20

72. Blood flow regulation
a. cerebrum > cerebellum > sp. cord
b. sp. cord > cerebellum > cerebrum
c. cerebrum > sp. cord > cerebellum

73. N2O shd not be used in elderly with intestinal obs d/t:
a. risk of inc distension

74. Cylinder half filled with liquid N2O. Pressure in the cylinder?

75. Pressre of N2O cylinder is 750 psi. Pressure in the cylinder till the last drop evaporates?

76. T1/2 N2O ?
a. does not undergo metab and is exc unchanged

77. Myocardial toxicity to a L/A?
a. Bupivacaine

78. cardiovascular collapse
a. bupivacaine

79. MetHbemia
a. Prilocaine

80. Fracture 5, 6th rib. longest acting L/A to be given
a. Bupivacaine

81. MAC related to:
a. Bl / gas solubility
b. oil / gas solubility
c. alveolar air conc.

82. Hyperoxia. All true except 1.
a. retrolental fibroplasia
b. atelectasis
c. dec surfactant prod
d. CV depression
e. anemia

83. PG released in inflammation are inhibited by:
a. aspirin
b. corticosteroids
c. serotonin

84. Muscle relaxant that can be given to an asthmatic pt
a. atracurium
b. tubocurare
c. cisatracurium
d. suxa

85. Muscle relaxant, renally exc, long duration of action
a. tubocurare
b. vancuronium
c. pancuroniun
d. gellamine

86. For disinfection hands shd be washed with
a. phenol
b. alcohol with chlorhexidine
c. formaldehyde

87. The operating room shd b cleaned with the following drug, following surgery of HIV pt:
a. 10% gluteraldehyde
b. 1% phosphoenol
c. 2% gluteraldehyde
d. H2O2

88. Following is true regarding sterilization:
a. repeated heating denatures polyvenyl tubings
b. autoclaving is heating objects at 121 degC at 15 psi for 3 min
c. radiation (UV light)
d. dry heat
e. formaldehyd

89. Reason for heat generation when CO2 is passed thru soda lime
a. formation of CaCO3
b. CaO formation
c. friction b/w soda and CO2

90. Flowmeter stops working when
a. flow of N2O > O2
b. flow of O2 > N2O
c. breakage / disruption of control valve.

91. Laminar flow (MURAD QS)
a. flow directly prop pressure
b. resistance independent

92. When Rynolds no. exceeds 3000
a. viscosity dec
b. density dec
c. velocity dec

93. Flow meter
a. used towards expiration
b. kept vertical to keep the dial needle at zero
c. not affected by humidity
d. cannot be attached to the ventilator

94. Regarding transducer all are true except
a. changes signal from 1 form of energy to another
b. capacitanc transducer can be used on body

95. Movement of molecules from high conc they layer/ surface:
a. diffusion
b. osmosis
c. doppler effect

96. Critical temp is:
a. the temp at which gas must be cooled to become liquid

97. Latent heat of vaporization:
a. temp at which liquid converts to vapour / gas without the utilization of external heat
b. becomes zero with gain of energy

98. Relation of vol of a subs to its weight is:
a. density
b. viscosity
c. conc

99. To convert Celcius scale to Farenheit scale:
a. 9/5 *F- 32
b. 5/9 *F x 32
c. 5/9 *F + 32
d. Subract 32 and multiply by 5/9
e. add 32 and multiply by 9/5

100. Pt lying uncovered in operating room. Max heat is lost by:
a. Conduction
b. convection
c. radiation
d. evaporation

101. Pt with ETT tube. Heat is lost by:
a. Conduction
b. convection
c. radiation
d. evaporation

102. As the gas flows thru the vaporizer
a. gas is heated
b. outside of the container is cooled
c. surface vapour with highest energy is evaporated

103. Humidity is measured by:
a. hygrometer
b. thermometer

104. Apart frm measuring end tidal CO2 conc., capnograph can also measure
a. CO2 saturation
b. PO2
c. reduced Hb
d. oxyHb

105. Regarding Capnograph
a. rise of baseline indicate failure of valve
b. rise of height indicate valve failure

106. O2 is measured by all techniques except ......................(MURAD QS)
a. mass spectrometry

107. alpha waves with eyes closed
a. convert to beta when eyes open
b. convert to delta in REM
c. followed by slow frequency, high altitude wave

108. During diathermy when neutral plate is disturbed: ( Burn inc as current density inc, but independent of freq )
a. pt may get a burn even at ECG electrodes ( Burn can occur at all frequencies )
b. depends it is operating at cutting or coagulation mode
c. depends on current frequency

109. Strong magnetic instruments may not be used in a remote village d/t side effects. Instrument that can be used is:
a. CT scan
b. MRI
c. Angioplasty

110. Resistance in series:
a. inc as the wire is stretched
b. known as strain gauge used as pressure transducer
c. proportional to current flow

111. Wheatstone bridge
a. measures changes of resistsnce
b. no current flows when bridge is balanced

112. Pulse oxymetery
a. signals occur at 0.5 sec
b. light emitted by filtered light source

113. Variance is related to:
a. variability
b. square root of std deviation
c. range

114. Which measure of central tendency is used most frequently in clinical practise
a. mean
b. mode
c. median
d. 50th percentile
e. Wilcoxon rank sum test

115. t-test
a. shows relation of 2 paired means

116. Surgeon treats 200 pts of heamorrhoids. He randomly divides the pts into surgically treated and pharmacologically treated groups. After 1 yr he reasses the pts and finds that surgically treated pts have better outcome. This is called:
a. case - control study
b. cohort study
c. prospective cohort
d. randomized control trials

117. Treatment of strep pneumonia by sulphonamide and penicilline by random selection is called:
a. single blind
b. double blind
c. tripple blind

118. O2 carried most in fetal circ.
a. Umblical artery
b. Umblical vein
c. Superior vena cava
d. Aorta

119. Esophagus histology
a. covered by squamous ep
b. has str. sq in upper 1/3
c. has str. sq. in lower 1/3
d. has 3 layers of muscles
e. esophageal opening acting as anatomical sphincter

120. Length of larynx.
a. 15 cm average
b. cricoid to T2 cartilage

121. Esophageal opening
a. at left crus of diaphragm
b. Left phrenic nerve also passes thru this opening
c. at level of T12 vert
d. acts as anatomic sphincter to the stomach

122. Pt complains of chest pain for more than 30 min . ECG shows changes in V1- V4. It denotes:
a. anterior wall MI
b. anterolateral MI
c. Inferior wall MI
d. Lateral wall MI
e. Inferior wall MI

123. Groove for subclavian artery at
a. clavicle
b. 1st rib
c. 2nd rib
d. 6th rib

124. Structures entering thorasic inlet
a. accessory nerve
b. aorta
c. superior vena cava
d. azygous vein
e. Left recurrent laryngeal nerve

125. Diaphragm is directly not attached to:
a. T10 vertebral body
b. L1 vertebral body
c. xiphisternum
d. 10th rib

126. Fibrous pericardium and parietal layer of serous pericardium is supplied by
รค. phrenic nerve
b. cardiac plexus
c. esophageal plexus
d. intercostal nerves

127. Needle inserted at 5th intercostal space on the left of the sternum pierces:
a. internal intercostal muscle
b. internal membrane
c. left atrium
d. left ventricle
e. right ventricle

128. Which is untrue. 1st branch of ascending aorta is:
a. RCA from anterior aortic sinus
b. LCA from arch of aorta
c. left subclavian

129. 2nd heart sound is produced d/t :
a. closure of aortic and pulmonary valves

130. S2 splitting occurs d/t
a. delayed closure of pulmonic valve

131. Spinal cord ends at the level of lower border of:
a. L2 vertebra
b. L3 vertebra
c. L4 vertebra
d. L5 vertebra
e. S1 vertebra

132. Which is a branch of posterior division of sacral plexus
a. pudendal nerve
b. posterior cutaneous nerve of thigh
c. common peroneal nerve
d. nerve to quadratus femoris
e. perforating cutaneous nerve

133. Aortic pressure tracing is highest at which phase of cardiac cycle:
a. isovolumetric relaxation
b. rapid ejection phase
c. slow ejection phase
d. isovolumetric contraction

134. Muscle of quiet inspiration
a. diaphragm

135. Damage to pneumotaxic centre leads to:
a. apneusis
b. deep inspiration
c. short expiratory phase
d. irregular breathing
e. apnea

136. Thich filaments:
a. actin
b. myocin
c. tropomyocin
d. actin and myocin
e. troponin

137. Example of carrier mediated counter transport:
a. Na- glucose transport

138. Depolarization of cell is maintained by:
a. Na influx

139. Inhaled foreign body lodges in which part of lung
a. Rt apical bronchus

140. At the end of expiration:
a. intra-alveolar pressure is subatmospheric
b. intra-pleural pressure is subatmospheric

141. Action potential thru large nerve fiber:
a. 300 ms
b. 30 ms
c. 3 ms
d. 0.3 ms
e. 0.03 ms

142. Blow to the lateral surface of knee joint damages:
a. medial meniscus, medial collateral lig and anterior cruciate lig.

143. Knee joint is supplied by:
a. L3-L4

144. Vagus forms the efferent pathway of:
a. Hering- Breur reflex
b. J- receptors of pulmonary capillaries
c. Bain Bridge reflex

145. Leftwatd shift of oxy-Hb curve is called:
a. Bohr effect
b. Haldane effect
c. Chloride shift

146. Ventilation perfusion mismatch in which Ventilation > Perfusion is called as:
a. shunt
b. dead space

147. Most important buffer is interstitial fluid
a. Hb
b. H2CO3
c. H2PO4
d. Proteins

148. Damage to what part of brain will result in central cease of respiration
a. medulla

149. Pacinian corpuscles related to
a. touch
b. vibration
c. pressure
d. rapidly adapting pain
e. slowly adapting pain

150. Medullary respiratory group of neurons part of ascending reticular system
a. True
b. false

151. Anion gap increases in:
a. Uncontrolled DM

152. Bile from liver is different from that from GB in:
a. has more HCO3-
b. has more mucous and pigments
c. has more anions

153. Dry mouth increases all except
a. thrist
b. ADH
c. Ag II
d. Plsma osmolarity
e. Plasma vol

154. H* sec from nephron is inc by
a. acidosis
b. alkalosis

155. Coronary blood flow is maintained by:
a. autoregulation

156. Increased filtration thru capillary is fascilitated by:
a. Inc plasma colloid osmotic pressure
b. inc hydrostatic pressure of cap
c. inc hydrostatic pressure of ISF
d. inc oncotic pressure of ISF

157. General anesthesia influences
a. motor is affected 1st
b. pain neurons blocked 1st
c. sensory neurons blocked 1st
d. autonomic neurons blocked 1st

158. Middle cerebral artery supplies
a. leg foot area of motor and sensory cortex.......... true / false

159. Stretch reflex afferent 1a fibers .................... true/false

160. Mediators of inflammation
a. C3a
b. C5a
c. IL1
d. TNF alpha

161. Largest total cross-sectional and surface area is of:
a. artery
b. arterioles
c. capillaries
d. venules
e. veins

162. Blood flow regulation is mediated by:
a. arterioles
b. precepillary sphincter
c. capillaries
d. venules

163. If heart rate is 80 beats/min
a. duration of PR interval wld be b/w 0.12 - 0.16 sec

164. Lung function that cannot be measured by spirometry:
a. Residual vol

165. FRC = ?
a. ERV + RV

166. Hypoglycemia increases
a. SSK
b. Somatostatin
c. Gastrin
d. VIP
e. Secretin

167. Gastric acid is stimulated by:
a. Gastrin
b. CCK
c. Secterin
d. GIP
e. VIP

168. Somatostatin dec sec of which hormone
a. ADH
b. Insulin
c. Oxytocin
d. Prolactin
e. Thyroid hormone

169. A postmenopausal women suffered fracture d/t osteoporosis. Her Ca** is Inc, PO4 is dec. Reason?
a. Estrogen
b. Cortison
c. PTH
d. CRF
e. Calcitonin

170. Physics... Capacitance

Medicine March 2008

PREPARED BY: DR:MUHAMMAD SHEERAZ AKHTAR SOOMRO

1] Which one of the following is COX-II INHIBITOR?
A} Aspirin
B} Ibuprofen
C} Indomethacin
D} Meloxicam
E} Piroxicam

2] Which one of the following vitamin deficiency causes HOMOCYSTENURIA?
A} Vitamin B1
B} Vitamin B2
C} Vitamin B6
D} Vitamin B12
E} Biotin

3] Which one of the following structures is present at free edge of LESSER OMENTUM?
A} Bile duct, cystic artery, portal vein
B} Bile duct, hepatic artery, portal vein
C} Hepatic vein, hepatic artery, portal vein

4] A 16 year old boy was given CO-TRIMAXAZOLE for fever, after few hours he developed red color urine, likely abnormality is in
A} Glucose-6-Phosphate deficiency
B} Immune hemolysis
C} Paroxysmal Nocturnal Haemoglobinuria
D} Malaria
E} Sickle cell disease

5] Thiamine deficiency causes
A} Peripheral Neuropathy
B} Pellagra
C} Chelosis
D} Dermatitis

6] Milk is notoriously deficient in
A} Vitamin C
B} Iron
C} Riboflavin
D} Pantothenic acid
E} Vitamin A

7] Dry heat kills the bacteria by
A} Coagulation of proteins
B} Cell lysis
C} Free radical formation
D} Direct killing
E} Oxidation

8] Virus damage the cell by
A} Making the pores in cell membrane
B} Forming free radicals
C} Altering the formation of proteins
D} Nuclear damage
E} using energy for their own metabolism

9] Which one of the following lipoprotein has highest protein content?
A} HDL
B} LDL
C} VLDL
D} IDL
E} CHYLMICRONS

10] All are related to PLATELET FUNCTION EXCEPT
A} Capillary resilience test
B} BT
C} Clot retraction

11] ALLELLE is:
A} Fragmented genes
B} Non-identical genes
C} Structural genes
D} Regulatory gene
E} Autosomal Dominant gene

12] D.I.C is stimulated by:
A} Factor X
B} Factor XII
C} Thromboplastin
D} Factor IX
E} Fibrinogen

13] In parenchymal cells Iron is deposited in the form of
A} Tranferrin
B} Ferritin
C} Heamatin
D} Heamoglobin
E} Lipifuscin

14] a mother is having blood group A+(Ao, DD), father is having blood group B+(Bo, Dd). Which of the following blood group cannot be inherited by their children?
A} A+
B} B+
C} AB+
D} AB-
E} O+

15] The person has suffered the injury to spinal cord leading to HEMISECTION of the cord, the IPSILATERAL sign will be
A} Loss of pain
B} Loss of temperature
C} Loss of sensation of touch and vibration
D} Lower motor neuron paralysis
E} Upper motor neuron paralysis

16] Valve less vessel is
A} Aorta
B} Pulmonary artery
C} Coronary Sinus
D} Pulmonary Trunk
E} SVC

17] A lady has undergone colostomy is now on the TPN. She is prone to develop:
A} Hyperglycemia
B} Hypocalcaemia
C} Hypophosphatemia
D} Hyperviscosity
E} Hypoglycemia

18] Turner syndrome
A} XXY
B} 45XO
C} 46XY
D} XXX
E} 69XX

19] Regarding Von Willbrand disease
A} Autosomal Dominant
B} Autosomal Recessive
C} Some family members have low level of Factor IX
D} Some family members have abnormal level of Factor IX
E} has positive family history

20] Which of the following condition is related to lymphatics?
A} Angiosarcoma
B} Rhabdomyosarcoma
C} Cystic hygroma

21] The condition in which pulmonary trunk fails to divide leading to

A} PDA
B} Truncus arteriosus
C} TOF

22] Basal Cell Carcinoma is located at
A} Lower lip
B} Upper lip
C} Tongue
D} Hard palate
E} Soft palate

23] All are branches of Vagus Nerve except
A} Auricular Nerve
B} Lacrimal Nerve
C} Recurrent Larengeal Nerve
D} Internal Larengeal Nerve

24] Permanent Atrophy is caused by
A} Loss of Innervation
B} Hormonal Deficiency
C} Immobilization
D} Nutritional deficiency
E} blockage of arterial supply

25] Which of the following is not Carcinogen?
A} Alcohol
B} Benzathracine
C} Cyclophosphamide
D} Benzidine
E} Dimethylsulfate

26] The Initial step in APOPTOSIS is
A} Inhibition of P53 genes
B} Activation of BCL-2
C} Activation of Caspases
D} pores formed by lymphocytes

27] Which of the following is content of Cavernous Sinus?
A} Oculomotor
B} Trochelear
C} Abducent
D} Trigeminal (V3)

28] Which part of kidney produces ERYTROPOITEN
A} Macula Densa
B} Peritubular Capillary
C} PCT
D} DCT
E} LOH

29] A patient with signs and symptoms of megaloblasstic anemia. The likely cause is
A Decreased GIT motility
B} Deficiency of intrinsic factor
C} Malabsorption

30] Stimulation to increase Serum Calcium is
A} Hypo-phosphatemia
B} Paratharmone
C} Decreased ECF

31] Malnutrition causes all of the following EXCEPT
A} Pitting Edema.
B} Loss of subcutaneous fat.
C} Failure to thrive.
D} Skin pigmentation
E} Thrombocytopenia

32] Liver biopsy from a patient shows a lesion which comprises of central collection of structure less material surrounded by epitheliod cells and lymphocytes. One large cell with multiple nuclei arranged close to membrane is also seen. The most likely change in central area would be:
A} Caseous necrosis
B} Coagulation necrosis
C} Fatty changes
D} Hydropic changes
E} Liquefective necrosis

33] A 28 year fisherman presented with slowly developing lethargy, easy fatigue and palpitations. His diet comprises of fish and rice only. Physical examination: Pallor, Loss of touch sense in both feet and legs Hb: 7.5 gm/dl, Platelet count: 110 x 10 9/L. Reticulocyte count: 0.5%. Stool DR: Ova of Intestinal parasite. The most likely causative parasite is
A} Ankylostomata Duodenale
B} Ascris Lumbricoidis
C} Diphylobothrium Latum
D} Strangyloids Stercoralis
E} Taenia Saginata

34] A 40 year old male after road traffic accident had received massive blood transfusion. He is expected to have all EXCEPT
A} Hypocalcaemia
B} Hypokalemia
C} Hypothermia
D} Left shift of Oxyheamoglobin dissociation curve
E} Metabolic acidosis

35] The endothelial molecules ICAM-1 & VCAM-1 are responsible for
A} Direct endothelial injury
B} Endothelial cell contraction
C} Junctional retraction
D} Leukocyte adhesion
E} Leukocyte margination

36] Eating raw or under cooked meat can cause infestation by
A} Dracunculous Medinensis
B} Echinecoccus Granulosis
C} Liver Fluke
D} Schistosomiasis
E} Tape Worm

37] A pt: has sustained burn that is very painful with blisters. Healing of this burn will take place from which of the following layers of the skin
A} Basal layer of epidermis
B} Keratinized layer
C} Layer of upper dermis
D} Lower dermis
E} Subcutaneous layer

38] A 40 year old male presented with jaundice and generalized itching. His LFT shows Direct Billirubin 11 mg/100 ml, SGPT 75U/L, Alkaline Phosphate 2300 IU/L 500IU/L. The most likely cause is
A} Drug induced jaundice
B} Extra hepatic Cholestasis
C} Autoimmune Hepatitis
D} Alcoholic Hepatitis
E} Intrahepatic Cholestasis

39] The tissue damage by Ionization Radiation is due to
A} Damage to Golgi bodies
B} Formation of free radicals
C} Hydropic degeneration
D} Metaplasia of cell
E} Swelling of cells

40] Formation of free radicals cause by
A} Ionization Radiation

41] Edema of renal origin is most likely due to
Albuminuria & sodium retention
B} Decreased water excretion
C} Hypertension
D} Renal stone
E} Sodium retention by the kidney

42] Increase in Light Chain Immunoglobulins Is the characteristic feature of
A} Endocrine type Amyloidosis
B} Hereditary Amyloidosis
C} Localized type Amyloidosis
D} Reactive Amyloidosis
E} Systemic type Amyloidosis

43] Chemotaxis is caused by
A} C5a
B} C5b
C} Lymphokines
D} Leucotriene B3
E} Opsonins

44] Following are the actions of Archidonic acid metabolites in inflammation EXCEPT
A} Chemotaxis
B} Increased vascular permeability
C} Thrombosis
D} Vasoconstriction
E} Vasodilatation

45] A 65 year old male pt: presented with chest pain for last 30 mins. And has ST segment elevation in LEADS V1 to V4. He is most likely to have
A} Anterior infarction
B} Anterolateral infarction
C} Anteroseptal infarction
D} Inferior Infarction
E} True Posterior infarction

46] A female at 30 wks of gestation has Hb: 9.0 g/dl with normocytic normochromic picture. The blood condition is most likely due to
A} Iron deficiency
B} Decreased bone marrow activity
C} Folic acid deficiency
D} Increased placenta size
E} Plasma Volume Expansion

47] The Sensations of Anterior Triangle of the neck is mediated through
A} C1, C2, C3
B} C1, C2, C3, C4
C} C2, C3, C4
D} C2, C3s
E} C1, C2

48] All are features of IRREVERSIBLE cell injury EXCEPT
A} Karyolysis
B} Karyorhexis
C} Autolysis
D} Shrinkage of mitochondria
E} Appearance of myelin figure

49] A young athlete has difficulty in flexion of knee and extension of hip. Which of the following muscle is likely paralyzed
A} Rectus femoris
B} Sartorius
C} Semitendinosus
D} Vastas lateralis
E} Popliteus

50] In the Aortic opening I the Diaphragm is constricted, which of the following structure will be compressed along with Aorta
A} Azygous vein and Vagus nerve
B} Thoracic duct and Vagus nerve
C} Thoracic duct and Azygos vein
D} Azygos vein and both phrenic nerves
E} Inferior vena cava

51] When the bulbur urethra wil injure, urine will leak into
A} Deep Perineal Pouch
B} Superficial Perineal Pouch
C} Fascia lata
D} Scrotum
E} Ischiorectal fossa

52] The most common site of fertilization in humans is
A} Ovary
B} Uterus
C} Fallopian tube
D} Cervix
E} Peritoneal cavity

53] The initial event in the transfer of RBC to site of inflammation
A} Margination
B} Emigration
C} Pavementation
D} Diapedesis
E} Phagocytosis

54] A semiconscious patient is brought to the emergency room. He has history of taking some unknown drug. NaHCO3 reverses the action of the drug. Which drug the pt. has likely taken:
A} Phenobarbital
B} Phenothiazine
C} Morphine
D} Diazepam
E} Alcohol

55] Within 1 hr of the Acute M.I, which of the following enzyme will be raised?
A} CK-MB
B} LDH
C} Alkaline Phosphatase
D} AST
E} Troponin T

56] Which organelle is not present at axon hillock
A} Microtubules
B} microfilaments
C} Mitochondria
D} RER
E} SER

57] Which is not related to embolus?
A} Liquid
B} Gas
C} Thrombus
D} Amniotic fluid
E} Fat

58] Which of the following muscle compensate for supinator?
A} Biceps Brachi
B} Brachialis
C} Brachioradialis

59] A patient presented with anterior wall M.I Artery involved is

A} LAD

60] Which of the following molecule easily crosses Blood Brain Barrier?
A} CO2
B} H2O

61] Hypervitaminosis A cause

A} Ataxia
B} Anemia
C} Scaly Dermatitis

62] Hypertrophy indicates
A} Increase in size of cell
B} Increase in no. of cell
C} Decrease in no. of cell
D} Decrease in size of cell

63] Diabetic patient using Roziglitazone and metformin. Which investigation for follow up
A} Lipid profile + Renal profile
B} Renal profile + Hepatic profile
C} Renal profile + Hepatic profile + Cardiac
64] If the whole movement of Abduction of arm is lost the likely damage is in the Brachial Plexus
A} Upper trunk + Posterior cord
B} Upper trunk + Medial cord
C} Lower trunk + Posterior cord
D} Lower trunk + Medial cord

65] Cords of Brachial Plexus are named according to Relation with
A} Axillary artery
B} Subclavian artery

66] Myelination in CNS is done by
A} Schwann cells
B} Oligodendrocytes
C} Astrocytes
D} Microglia cells

67] Captopril
A} can be given in large doses in hypertensive crisis

68] Which of the nucleus is NOT related to Facial Nerve?

A} Main Dorsal Nucleus
B} Nucleus of Tractus Solitarius
C} Nucleus Ambiguas
D} Sensory nucleus

69] Platelets
A} Are formed from precursor cells in the bone marrow
B} Has no nucleus

70] Primary auditory cortex is present in
A} Occipital lobe
B} Superior Temporal Gyrus
C} Frontal lobe
D} Prefrontal lobe

71] Patient is suffering from factor VIII deficiency
A} Genetically Engineered Factor VIII is available

72] Most Common cause of Thyrotoxicosis

A} Graves disease
B} Solitary nodule
C} Toxic nodular goiter
D} Diffuse goiter

73] Which of the following is involved in maintaining RESTING MEMBRANE POTENTIAL?
A} Outward Potassium current
B} Outward Sodium current
C} Inward Sodium current
D} Inward Chlorine current
E} Sodium/potassium ATPase Pump

74] Heart sound produced by rapid ventricular filling is
A} 1st heart sound
B} 2nd heart sound
C} 3rd heart sound
D} 4th heart sound
E} 5th heart sound

75] A patient presented with vertical diplopic, head tilting, and also difficulty coming downstairs the likely nerve damaged is
A} Oculomoter nerve
B} Trochlear nerve
C} Trigeminal nerve
D} Optic nerve
E} Abducent nerve

76] Substance has to cross semi permeable membrane in simple diffusion
A} Is not saturable
B} Require carriers
C} Require energy

77] Carcinoma prostate drain into
A} Para-aortic nodes
B} External iliac nodes
C} Internal iliac nodes
D} External and internal iliac nodes

78] Pulmonary capillary wedge pressure is so
A} Catheter used is wedge shaped
B} Is direct measurement of left atrial pressure
C} Is direct measurement of Right atrial pressure

Sunday, November 18, 2007

RADIOLOGY OCT 2007

BY KASHIF NADEEM
NISHTAR HOSPITAL,MULTAN


1-The muscle involved in unlocking of knee joint is:
Poplitus,Rectus femoris,Plantaris.Soleus
2-Adult derivative of notochord is:
Nucleus pulposis,Annulus fibrosis,Vertebre,Vertebral canal
3-Vertebrae is derived from:
Myotome,Sclerotome,Dermatome,Ectoderm,Endoderm
4-Memory centre is located in:
Insula,Parietal lobe,Temporal lobe,Frontal lobe
5-The most commom type of salivary gland tumor is:
Salivary glands,Parotids,Submandibular,Sublingual
6-Distruction of Ant.pituatary gland causes dec.functioning of
Glom.fasiculata,Glom.granulosa,Medulla,Adrenal cortex
7-Least chances of renal stones is associated with:
Hyperlipidemia,HyperPTH,Hyper vit.D,Infections,Hyperurecimia
8-Nerve supply to extensors of arm is supplied by:
Lat.cord,Medial cord,Post cord,Lateral and medial cord
9-Nerve injured in Ant.disloacation of Shoulder joint is:
Musculocutaneous,Axillary,Median,Radial,Suprascapular
10-Damage to scaphoid bone causes injury to:
Radial A.Ulnar A.Brachial A,Ant.interosseous A.
11-Common site of fracture at rib is:
Angle,Shaft,Costochondral joint,tubercle
12-Following is not a tumor marker:
PLAP,CEA,bHCG,AFP,Acid Phospatase
13-Most common histology found in lung tumors is:
Squamous,AdenoCA,Mixed,Small CA
14-Patients comes with Rt.deviation of tongue,Dec.sense of touch and vibartions,the artery
commonly involved in brain is:
PICA,AICA,Ant.Spinal,Post.Cerbral,Sup.Cerbral A.
15-Soldier comes with heavy bleeding,the ideal fluid replacement would be:
Packed RBCs,Crystallines,Colloids,Whole blood for 3 days,Whole blood for 18 days
16-Maxillary sinus opens into:
Sup.meatus,Inferior meatus,Middle meatus,Nasal septum
17-Patient having increased levels of IgE,most probably suffering from:
Bacterial inf,Viral inf,Parasitic inf,Fungal inf.
18-Autospy done on the patient having CRF,most prabable finding would be:
Hypertrophied PTH gland,Hypertrophied adrenals,Hypertrophied pituatry,Hypertrophied thyroids
19-Excitation of post.pituatary would cause:
Sweeting,Stress,Shivering,Hunger pangs
20-Foetal period starts after which week:
11th.8th,12th,16th,21st
21-Patient having dec levels of factorII,VII,IX,X,most likely have:
Dec.antithrombin III,Dec Vit.K
22-Young pt.having Hb:6.0,TLC:3.5/ul,Plts:1lac is suffering from:
Iron def.,Folate def.,Vit B12 def.,Aplastic anaemia
23-Nucleus ambigus supplies to:
Teeths,Jaw,Tongue,Lyrnx
24-Olfactory area is present in:
Ant.perforating material,Occipital lobe,Inf.temporal gyrus,Parietal lobe
25-Patient with injury to left 8th cervical segment of spinal cord will not show following sign:
Dec sense of position,vibration below lesion on same side,Extensor plantar on left side,Dec
power of muscles below the leson on same side,Dec sense of pain and temprature below the
lesion on same side.
26-Feature of Rickets and Osteomalacia is:
Inc.Vit D,Inc.Ca,Inc PTH,Dec.bone density
27-Most common site of malignancy in pts suffering from nuclear outbreak
Haematopoitic,Thyroid,Lung,Breast,Bones
28-Virus acts on cells by:
Damaging cell membrane,Damaging nuclear membrane,Invloving protien synthesis
29-Most sensitive cells to hypoxia are:
RBCs,Neurons,Nephrons,WBCs,Platelets
30-Myelin in CNS is formed by:
Microglia,Schawan cells,Oligodendrocytes,Astrocytes
31-Feature not associated with irreversible cell injury is:
Mylein figures,Karyolysis,Karyorrehxis,Mitochondrial shrinkage
32-Ureter isnot constricted at:
Pelvic brim,at PUJ,Psoas muscle,Openning at bladder
33-Common relation of ureter is:
Ant.to gonadal vessels and post.to iliac A.,Post.to gonadal vessels and ant.to iliac A.
34-Patient feels pain after she underwent surgery for fibroids,structure injured would be:
Ureters,Ovaries,Fallopian tubes
35-Least common site for ectopic pregnancy would be at:
Ovaries,Pouch of douglus,Greater omentum,Fallopian tubes,Cervix
36-Gall bladder is supplied by:
Cystic A and Left gastrcA.,Cystic A and Left Hepatic,Only Cystic A.
37-Venous drainage of urinary bladder is into:
Internal Iliac V.,External Iliac V.,Commom Iliac V.,Internal and external V.
38-Hypothyroid patient in on thyroxine,best marker to monitor his thyroid status is:
T3,T4,TSH,T3 and T4,T3,T4 and TSH levels
39-Patient having hyperplastic bone marrow,anaemia,Inc Platelets is probably suffering from:
Aplastic anaemia,Megaloblastic,Myelofibrosis,Leaukemia
40-Stimulus for Eryrthropoiten secreation is:
Hypoxia
41-Erytropoiten is always raised in:
Polycythemia vera,Primary polycythemia,Sec.polycythemia
42-Following vein would be dilated in portal HTN:
Inf.epigastric,Gonadal,Renal vein,Left colic V.
43-Patient after gastrectomy is on VitB12,the cells lost in the gastrectomy are:
Mucous,parietal,cheif,Goblet cells.
44-Fat tags attached to the walls of large intestine are known as:
Taenia coli,Hausstral folds,Appendeces epiplocea
45-Bile salts are reabsorbed from the:
Duedenum.Jejunum,Ileum,Colon,Rectum
46-Following is an autosomal disease is:
Cystic fibrosis,Hereditary spherocytosis,Thalasemia,Sickle cell anaemia
47-Type of defect in Heredetary spherocytosis is:
Enzymatic defect,Structural defect
48-Patient with jaundice,anaemia,high reticulocyte count is having:
Folate def.,Iron def.,VitB12 def.,Hemolytic anaemia
49-Ejaculatory duct opens into:
Ureter,Ureteric crest,Bladder,Prostatic urethera
50-Terminal part of CBD in relation to pancrease is:
Embeded into pancrease,lie posteriorly,lie anteriorly
51-Following would ause massive infarction and destruction leading to patient death:
Thrombus,Embolus,Fatty thrombus,Thromboembolism
52-22yrs female pt.with 13th week of pregnancy after having crush fractures in RSA dies after 3
days,most likely cause of death is:
Amniotic fluid embolism,Air embolism,Fat embolism
53-Patient with old history of adenoCA of colonis operated for polypectomy,on histologic evaluation
pathologist labelled it as benign growth with no chances into malignant transformation,it would be:
FAP,Villous adenoma,Tubular adenoma,Tubulovillous,Metaplastic polyp
54-Tyrosine derivateve doesnt include:
TSH,Adrenaline,Nor adrnaline,Prolactin,Dopamine
55-Precursor of steriod hormone is:
Progesterone,Pregnenolone,Cholesterol
56-Capsule of liver in known as:
Disse,Glissons
57-Most common site of thyroglossal cyst is:
Suprahyoid,Infrahyoid,Hyoid
58-Wasting of thenar eminence,loss of sensation over thumb and index finger,nerve involved is:
Median,Axillary,Radial,Ulnar
59-The base of urinary bladder is made by:
Post surface,Ant surface,Inferolateral,Superior surface
60-Shock without having vasodilation is likely associated with:
Burns,Gram positive inf,Gram negative inf.,Superantigen infection
61-Following doesnt form the layer of inguinal canal:
External oblique,internal oblique,transversus,rectus abdominus.
62-Femoral sheath is formed by:
Fascia transversalis,Fasica trans.and Fasica iliaca,External oblique,Internal oblique
63-Patient with bone pains having normal Ca,inc Alk.phosp.most likely suffering from:
Pagets,HyperPTH,Hyper VitD,Bone mets,Osteomalacia
64-External spermatic fasica is formed by:
External oblique,Internal oblique,Cremastric muscle,Transversus muslce
65-In Turner syndrome,the genotype would be:
XX,XO,XXY,XY,XYY
66-Organ having least chances of infarction:
Lungs,Heart,Kidneys,Liver,Spleen
67-Type of necrosis in brain infarction:
Couglative,Liquefactive,Fat,Traumatic
68-Pt.with cervical lymphadenopaty,+ve AFB sputum,sign to look for TB on microscopy is:
Chronic inflammation.caseous necrosis,lymphocyctic infiltartion
69-Thyroid gland moves with swallowing because it is enclosed in:
Pretracheal fasica,Investing fasica,Vertebral fascia,Carotid fascia
70-Neurovascular bundle in chest wall lies between:
External and Internal intercostal mucles,Internaland Innermost layers,Innermost and enothoracic
fasica,Beneath Endothoracic fascia
71-Fibrous pericardium and medicatinal pleura is supplied by:
Vagus N.,Intercostal N.,Phrenic N.,Autonomic N.
72-Man is suffering from testicular ca,the lympahtic drainage of testicle is into:
Para aortic L.nodes,Pre aortic,Superficial inguinal,Internal iliac,External iliac L.nodes
73-In exercise,the venous blood returns to the heart by:
Muscle pump in calves
74-Circulation in heart is maintained by:
Symphthatic sys,Parasymphthetic sys,Local mechanism
75-Fisherman is presented with gingival bleeding and ecchymosis,he is suffering from:
Folate def.,Iron def.,Vit B12 def.,Vit C def.
76-Facor affecting collagen synthesis during healing is:
Infections,Vit C,Foriegn body
77-Mesothelioma is associated with:
Vinyl chloride,Silica,Asbestos,Copper dust,Carbon
78-Child having meckels diverticulum is having bleeding per rectum,it is due to:
Volvulus,Interssusption,Ectopic gastric tissue
79-During lactation,Amenorrhea is due to:
Inhibition of LH and FSH thru Prolactin,Dec.prolactin,Dec oestrogen
80-Presence of pancratic tissue in gastric mucosa is termed as:
Hamartoma,Metaplasaia,Neoplasia,Choristoma,Dysplasia
81-Main difference between primary and secondary intention wound healing is:
Granulation tissue,Wound contraction,Inflammatory cells
82-Child with sore throat after 3 weeks developed oedema,haemturia,cause would be:
Minimal change disease.post streptococcal GN,IgA nephropathy,Focal segmental GS.
83-Microscopic feature of polyarterites nodusa is:
Granuloma,Fibrinoid necrosis
84-Angiotension II exerts its effects by activating:
Renin,Angiotension I,Aldosterone,ANF
85-Tumor compressing optic chiasma would cause:
Binasal haemianopia,Bilateral haemianopia,Bitemporal haemianopia,Complete blindness
86-Growth hormone is maximally rasies in:
Sleeping,Excercise,Hunger,Anxiety



BY KASHIF NADEEM
NISHTAR HOSPITAL,MULTAN

Saturday, November 3, 2007

OBST&GYNEA FCPS-1(OCT 23 07) Q & A’s- contributed by Dr.Ashh & Dr.Huma

1.Which of the following does not form the wall of perineum

A.coccyx
B.pubic symphsis
C.ishcial tuberosity
D.sacrotuberous ligament
E.sacrospinous ligament

2.A pt presented with pain on defecation after severe constipation.pain in constipation occurs due to ?
A.autonomic nerves
B.Internal pudendal artey
C.pudendal nerve
D.perineal nerve
E.inguinal nerve

3.Lymph drainage of perianal skin is from one of the following

A.internal iliac nodes
B.external iliac nodes
C.lateral group of horizontal superficail nodes
D.medial group of horizontal superficail nodes
E.vertical group of nodes

4.Lesser omentum
A.connects with deudenum
B.forms falciform ligament
C.related to left adrenal gland
D.related to left kidney
E.related to rt kidney

5.A young girl of 25 yrs went with her husband on honey moon after one month of marriage.she suddenly experianced severe spasmotic pain in her rt iliac fossa.n presented in emergency in state of shock.most probable diagnosis is
A..acute appendicitis
B.renal colic
C.intestinal obstruction
D.ectopic Pregnancy
E.acute cholecystitis

6.which of the following structure is not palpable through vagina
A.cervix
B.rectum
C.ureteric stone
D.retrouterine pouch
E.vesicouterine pouch

7.The peritoneum covers the anterior abdominal wall which is continous with the perineum.it has fascia which has superior n inferior layers.the inferior fascial layer also called as
A.colle's fascia
B.scarpe fascia
C.perineal membrane
D.....fascia
E......fascia

8.If a known hypertensive pt took some diuretic n died in 6 hours.wat is the cause
A.acute renal failure
B.chronic renal failure
C.diuretic use
D.hypophosphatemia
E.hypokalemia ?

9.Which of the following is not a feature of shock
A.decrease cardiac output
B.muslce weakness
C.increased urine output
D.tachycardia
E.restlessness

10.supply of sphincter urethra comes from
A.ilioinguinal nerver
B.pelvis splanchnic nerves
C.sacral splanchnic nerves
D.autonomic nerves
E.Pudendal nerves

11.Rt ovarian vein drains the following

A.inferior vena cava
B.superior mesenteric
C.inferior mesenteric
D.rt renal vein
E.left renal vein

12.What is most appropiate about uterine tube

A.moves laterally to open medialy in the ovaries
B.present at the base of broad ligament
C.is 6cm long in adults
D.has an abd ostiium which is 0.5mm when dilated
E.extend above the fundus of uterus

13.Genital tubercle in females give rise to

A.labia majora
B.labia minora
C.clitoris
D.vestibular glands
E.bulbourethral glands

14.urachal cyst is the remnant of

A.allantois
B.mekel's diverticulum
C.........
D.....
E.........

15.Thymus develops from

A.ectoderm of 2nd brachial pouch
B.endoderm of 2nd brachial pouch
C.ectoderm of 3rd brachial pouch
D.endoderm of 3rd brachial pouch
E.mesoderm of 3rd brachial pouch

16.A pt presented with an opening in the ant wall of sternocledomastoid muscle with pussy discharge coming out of it.this problem occured due to abnormality in one of the following

A.1st pharyngeal cleft
B.2nd pharyngeal cleft
C.1st pharyngeal pouch
D.2nd pharyngeal pouch
E.3rd pharyngeal cleft

17.Diaphragmatic hernia occurs due to

A. absence of pleuro-pericardial membrane
B. absence of septum transversum
C. absence of pleuro-peritoneal membrane
D. absence of central tendon
E. absence of arch?

18.Erythropoises occurs in middle trimester mainly from

A.liver
B.kidney
C.spleen
D.bone marrow
E.both liver n kidney
19.Superior parathyroid gland develops from

A.1st brachial arch
B.2nd brachial arch
C.3rd brachial pouch
D.4th brachial pouch
E.3rd brachial cleft

20.In cervical carcinoma,wat is the lymph drainage

A.internal iliac
B.external iliac
C.both internal n external iliac
D.superficial inguinal
E.deep inguinal

21.RT coronary artery

A.arises from anterior aortic sinus
B.enters the rt heart border after passing through sulcus on posterir surface
C. supplies both ventricles
D. supplies S.A node
E. supplies left atrium

22.Fat deposition n ductal development of breast is the function of which hormone

A.estrogen
B.progesterone
C.prolactin
D.oxytocin
E.hcG

23.Inhibition of ovulation is the function of which hormone

A.progesterone
B .prolactin
C.dopamine
D.estrogen
E.GnRH

24.Thirst is least stimulated by

A.decrease blood volume
B.angiotension 2
C.salt depletion
D.decrease plasma volume
E.blood pressure

25.Most imp hormone involve in gluconeogenesis is

A.growth hormone
B.insulin
C.thyroxine
D.cortisol
E. Glycogen

26.A pt presented with rt iliac fossa pain. he is diagnosed to have acute appendicitis on flexing his rt thigh inward n medially he cries with pain.wat is the type of appendicitis he has

A.paracolic
B.retrocolic
C.pelvic
D.paracecal
E.subcecal

27.which of the following structure has both intra n extra pelvic extension

A.broad ligament
B.ovarian ligament
C.transverse cervical ligament
D.round ligament of ovary
E.round ligament of uterus

28.Stab wound above the piriformis muscle will damage which structure

A.superior gluteal nerves?
B.inferior gluteal nerves
C.sciatic nerve
D.tendon of obturator internus
E.inguinal nerves

29.Nerve supply of rectum

A.hypogastric plexus
B.greater splanchnic nerves
C.pelvis splanchnic nerves
D.short spanchnic nerves
E. inferior mesenteric plexus
30.One slide of a specimen shows stratified squamous epithelium with vascular smooth muscle and elastic fibres most probably the specimen is

A.cervix
B.uterine tube
C.vagina
D.uterus
E.anus

31.Apoptosis is inhibited by

A.capsases activation
B. Bcl-2 inhibition
C. Activation of P-53
D. apoptosis related protein ??
E…


32.Most potent chemotactic factor is

A.C3a
B.C5a ?
C.IL-1
D.viruses
E.arachdonic acid metabolites

33.what is the most appropiate answer

A.C3a is opsonin
B.C5a is potent anaphylactic
C.C5a is a potent chemotactic agent
D.C3b n C5a are anaphylactant
E.......

34.Low serum complement seen in which condition

A.SLE
B.ankylosing spondiolitis
C.rheumatid arthritis
D.multiple sclerosis
E.dermatomiositis

35.Pt presented with photosensitivity,rash n joint pain.which is the daignostic in this case

A.anti SS antibodies
B.anti DS antibodies
C.RA
D.anticentromere antibodies
E.antimitochondrial antibodies

36.Most dangerous Side effect of estrogen therapy is

A. suppression of lactation
B. hirsutism
C.thrombophlebitis
D.osteoporosis
E..........

37.If a pt is on long term corticosteroid therapy.she wil most probably hav increased risk of

A.repeated infections
B.decrease wound healing
C.osteoperosis n fractures
D.........
E....

38.Platelets r stored at room temprature because

A.to optimise its function?
B.to maintain its number
C.to avoid allergic reaction
D. to increase number
E.....

39.Which is most imp indicator of muscle protein loss

A.urea
B.ammonia
C.none of above
D.uric acid
E. ?

40.wat is true about DNA

A.Double stranded in which two strands are antiparallel to each other
B. a single turn of DNA is 2nm
C.Can exist as helix in single stranded form as well as in Double stranded form
D.
E.
41.A normal looking Girl came to you with primary amenorrhea,on examination she was having short blind vagina wid normal vulva, scanty pubic n axillary hairs,normal breasts,absent uterus,her karyotype is?

A.46XY
B.47XY
C.47XXY
D.45XO

45.A pt came to you with primary amenorrhoea,webbed neck,short stature diagnosed as Turner syndrome, wht is her karyotype?

A.45XO
B.46XY
C.47XXY
D.46XX
E.......

46.Hydrolysis of DNA gives

A.proline
B.ribose
C.phosphoric acid?
D...
E...

47.Which of the following has highest cholesterol content

A. Chylomicron remnants
B. LDL
C. VLDL
D. HDL
E. IDL

48.Which hormone convert to its active form at target tissue with the help of 5 a reductase?

A. Testosterone
B.Estrogen
C.dihydoepiandosterone
D.Progesterone
E...

49.Which drug do not cause gynaecomasia?

A.Digoxin
B.Griseofulvin
C.Cimetidine
D.Androgen
E.spironolactone

50.Which is the best option in identification of Turner's syndrome

A.ultrasound
B.barr bodies
C.karyotyping
D.Ct scan
E...

51.Pyruvic acid is used as intermedite in which step of cell metabolism

A.carbohydrate to acetyl co A
B.glucose to acetyl co A
C.acetic acid to acetyl co A
D.......
E..

52.Epinephrine,norepinephrine n dopamine are derivatives of which aminoacid

A.alanine
B.arginine
C.proline
D.tyrosine
E.phenylalanine

53.End product of purine metabolism is

A.urea and water
B.uric acid
C.glucose
D.water and ammonia
E.ammonia

54.Erythropoitin is secreted from

A.liver cell
B.peritubular interstitium of kidney
C.macula densa of kidney
D...
E...

55.ESR is decreased with

A.temprature
B.albumin is decreased
C.globulin is decreased
D.decreased blood volume
E.decreased plasma volume

56.RBC's are

A.biconvex
B.nonfragile
C.have nucleus
D.largest of all cells
E.have glycolytic enzyme activity
57.Tamoxifen has effect on which system

A.CVS
B.CNS
C.breast
D.liver
E.kidney

58.Which of the following drug is most notorious for causing renal toxicity

A.cisplatin
B.cyclophosphamide
C.vincristine
D.blephamide
E.....

59.Commonest Cause of PDA

A.drugs
B.toxin
C.permaturity
D.congenital abnormality
E..infection

60.Most common Cause of metaplasia is

A.ultrasonography
B.chronic irritation
C.infections
D.radiations
E...

61.Wat is the differentiating point of hyperplasia fron hypertrophy

A.increase in size of cell
B.increase in size n no of cell
C.is reversible
D.is premalignant ?
E.involve viscera only

62.Dysplasia is seen mainly seen in

A.bone marrow
B.cartilage
C.epithelia
D.fibrous tissue
E.deep tissue

63.Wat is the differentiating feature of hyperplasia from benign tumor

A.increase in no of cell
B.are the same as parental cell
C.cytplasm n nucleus ratio is derranged
D....
E...

64.What is the most true among following

A.mRNA has a codon
B.mRNA has anticodon
C.rRNA is most abundant n involve as ribosomes on endoplasmic reticulum
D.tRNA is largest
E.tRNA involve in protein synthesis

65.deficiency of THAIMINE(B1)causes all except

A.cardiac anomalies
B.muscle wasting
C.defects in alcohlics
D.subacute degenaration of spinal cord
E.cns abnormalities in alcoholics

66.AIDS is associated with all of the following except

A.kaposi sarcoma
B.lymphoid tumors
C.primary tumor of brain
D.STD
E.leukemia

67.VITAMIN involve in collagen synthesis is

A.ascorbic acid
B.biotin
C.thiamine
D.pyridoxine
E.niacin

68.Neural tube defects occur due to deficiency of

A.iron
B.folic acid
C......

69.Iron is stored in the form of

A.ferritin
B.transferrin
C.apoferritin

70.CO2 is tranported in lungs through
A.simple diffusion
B.fasilitated diffusion
C.active transport
D.carriar proteins
E.channels

71.HSV is associated with
A.CA cervix
B.CA vulva
C.vaginal wart
D.vulval papules?

72.If a pt has presented with the wart on lateral wall of introitus.the most probable daignosis will be
A.fibroepithelial lesion
B.squamous cell CA of skin
C.polyp
D.squamous CA of vagina
E.HPV

73.Pt presented on 18th day of menstrual cycle her normal cycle is such dat she ovulates on day 14. Which phase will she be in?
A.follicular
B.ovulatory
C.pre mestural
D.proliferative
E.secretory?

74.Optic groove appears on left side of forebrain on day
A.12
B.22
C.32
D.42
E.52

75.Germen measles causes which abnormality. What is the most appropriate answer
A.congenital cataract
B.congenital deafness?
C,cardiac anomalies?
D.limb deformaties
E........

76.A newborn with anterior abd wall swelling and umbilical cord attached to it.wat is the condition called
A.omphalocele
B.gastroschiaosis
C.umblical hernia
D.omentocele
E.intestinal malformation

77.PT has exophthalmos n his T3 n T4 are increased.wat is the option for treatment of exophthalmos
A.drugs blocking the action of T4?
B.direct suppresion of T4
C.hypophysectomy
D.administration of testosterone
E.partial parathyroidectomy

78.Treatment of diabetes in pregnant lady is
A.sulphonyl urea
B.insulin
C.biguanides
D.suphonylurea n biguanides
E...

79.Statistical average applicable to the measurement of a population is
A.mean?
B.mode
C.median
d.standard deviation
e.central

80.Two groups one with CHD and associated risk factors is compared to another group with CHD but no associated risk factors. What type of study is it?
A. case control
B. cohort
C. prospective
D. retrospective
E. random

81.Oxytocin is given to a pt in labour.it has effect on:
A. oxytocin receptors on cervix
B.oxytocin receptor on myometrium and endometrium
C.dec prostaglandin recp on cervix
D.dec prostaglandin recp on myometriun


82.Beta lactum acts through
A.cell membrane
B.cell wall
C.DNA
D.30S
E.50S

83.side effect of streptomycin
A.impairment of hearing
B.
C.
D.
E.

84.Which of the following is opportunistic organism
A.E coli?
B.salmonella
C.shigella
D.klebsella
E.chlostridium

85.Psudomembranous colitis is caused by
A.Cl.difficile
B.Cl.tetani
C.CL perfiranges
D.Cl.botulinum
E..

86.About aspargillosis which is not correct
A.is caused by fungal
B.usually seen in preexisting lung diseases?
C.is caused by long term antibiotic use.
D...
E........

87.Most common cause of puerperal sepsis is
A.bacteriodes
B,E coli
C.trichomonas
D.chalymadia
E.gonorrhea

88.Another question associted with aspargilosis

89.Inutero infection is not caused by
A.syphlis
B.mumps
C.cytomegalovirus
D.HIV
E.rhinovirus

90.A pt with cervical lymphadenopathy. he has granuloma on histopathology.wat is the diagnostic finding in this case for T.B
A.AFB
B.caseous necrosis
C.montoux test
D.x-ray
E.......

91.A 25 yrs old multiparaous presented with lower abd pain.on histology it showed solid n cystic areas intermixed but on laproscopy it was semi solid with brown centre.wat is the most probable daignosis
A.dermoid cyst
B.endometrial cyst
C.ovarian CA
D.enodmetrial CA
E.teratoma

92.A pt presented with primary amennorhea.well developed secondary sexual characterstics,present breast but absent uterus.the organ not found is due to abnormal development of
A.mesonephric duct
B.paramesonephric duct
C.genital tubercle
D.........

93.A woman presented with vulvar itching n pinkish purulent discharge.wat is the cause
A.trichomanas vaginilis
B.chlamydia
C.gonorhea
D.lactobacillis
E....

94.presense of delta antigen shows( HDV)
A.Infectivity
B.recovery
C.Chronicity
D. Acute phase
E.Measure of severity/fatality of the disease

95.Most common organism involve in post operative abdominal & gynaecological infection is
A.E coli
B.bacteroides
C.chlamydia
D.trichomonas
E.gomorrhea

96.A pt presented with lower abd pain n purulent white dischrge.om laproscopy fallopian tubes were sticked together n ruptured during operation.wat is the condition involved
A.acute salpingitis
B.chronic salpingitis
C.pyosalpinx
D.hydrosalpinx

97.Pt has a history of infection 4 weeks back.now he developed same pain again.wat type of cell will present at this time of disease
A.neutophils
B.eosinophils
C.lymphocytes
D.basophils
E.mast cells

98.What is the drug of choice for DVT in ist trimester of pregnancy
A.aspirin
B.heparin
C.warfarin
D.indomethacin
E.mefanamic acid

100.Deficiency of Vit K will effect all of the following except
A.factor 7
B.factor 5
C.factor 9
D.fibrinogen
E.prothrombin

101.At which step intrinsic n extrinsic pathways converge
A.activater 10
B.activated 11
C.activated 12
D.prothrombin
E.activeted 9

102.Type 2 hypersensitivity reaction includes
A.erythroblastis fetalis
all other options were wrong

103.Transfusion reaction will not occur in a pt if we transfuse the
A.group A with O
B.group A with AB
C.group AB with A
D.group B with O
E.group O with B

104.Which of the following does not cross placenta easily
A.glucose
B.amino acid
C.Ig G
D.Ig M
E.CO2

105.Which drug is used in the treatment of hirsutism
A.antiandrogens
B.estrogen
C.testosterone
D.cryptoterone acetate
E.diacrone

106.Most common organism involved in infection caused by IUCD
A.actinomycosis
B.E coli
C.bacteroide
D.gonorrhea
E.trichomonas

107.ECF differ from ICF in
A.high conc. of Na n Ca
B.high K low Na
C.low Na n Ca high K
D. high conc. Of K & Ca with low Na
E.Volume …

108.diffrence of smooth n skeletal muscle
A.Ca-Calmodulin complex is present in smooth muscles

109.In partial mole,karyotype is
A.46XX
B.45XO
C.47XX
D.47XY
E.69XXY

110.If carbohydrate is separated from proteins wat will be the fate
A.aggregation n precipitation
B.eliminate fron kidney?
C.increase uptake int muscle

111.Lysozome contains
A.glucose
B.Ca
C.Na
D. hydrolases
E.alkaline phosphate

112.Which of the following does not have sulpha group
A.cysteine
B.cystedine
C.homocystine
D.methionine
E.threonine

113.What is not true about levator anni muscle
A.supplied by L1 n L2
B.puborectalis forms part of it

114.What is not true about ureter
A.enter the pelvis infront of common iliac artery
B.enter the bladder on superio lateral surface of trigone
C.not hav sphincteric valve at opening into bladder
D.can be palpated at pelvic brim
E.??
115. MCQ on Significance
A.

116. If a test is able to both diagnose and eliminate diseased and non-diseased wht is it called?
A.Specific
B.Accurate
C.Sensitive
D…

117. From a population two groups are selected on age basis and then subgroups are assigned randomly for the study.wht type of sampling is it?
A.Multistage sampling
B.Stratified sampling
C.Random stratified sampling
D.simple random sampling

118. Metabolic Alkalosis is caused by
a) Chronic Hypoventilation
b) Pancreatic Fistula
c) hyperglycemia
d) ATN

119.Q on Metabolic acidosis

120.Q on compensated respiratory alkalosis

121. For Rh blood transfusion to the anemic baby
A.crossmatch blood to babys plasma
B.Crossmatch blood to mothers plama
C.Crossmath blood to mothers blood
D.give wbc depleted transfusion
E.Give red cell concentrates crossmatched wid fetal blood

122. Following is Autosomal Dominant Disorder
a) Phenylketonuria
b) Hereditary Spherocytosis
c) Hemophilia A
d) Cystic Fibrosa

123. Source of Estrogen & Progesterone in last trimester is
a) Chorionic Villus
b) Placenta
c) Overy
d) Adenohypophysis
e) Corpus Leuteum

124. About K - Regulation , following is correct
a) K is 98% in the cells
b) normally completely reabsorbed in Distal tubule
c) increase water affects K-balance?
d) decrease in D.K.A

125.On examination of a female,a plaque like lesion seen on Postero-superior aspect of Vagina,it is
a) Squamous Cell CA
b) Adenocarcinoma
c) Rhabdomyosarcoma
d) wart?

Saturday, October 27, 2007

Medicine October 2007

Q.1 Paracetamol.....

a) increases PT
b) its overdose causes Nephrotoxicity
c) is a poor anti-inflamatory
d) is more stronger than codeine
e) causes met-Hb.emia more frequently than Phanacetin

Q.2 ATN is associated with...

a) Hyperkalemia
b) conc. urine in initial stages
c) increase in s.urea but normal s.creatinnine
d)

Q.3 Congenital cataract is associated with

a) chiken pox
b) chromosomal abnormality
c) small pox
d) Rubella

Q.4 MS is characterized by...

a) Lewy bodies
b) Patchy demylination & white fiber gliosis
c) axonal neuropathy
d)

Q.5 All of the following have ability of phagocytosis EXCEPT

a) Microgila
b) Lymphocytes
c) Kuffer cells
d) Neutrophils

Q.6 Pulmonary Arterial pressure increases with..

a) Essential HPTN
b) Sympthatic stimulation
c) Nitroglycerine
d) Excercise
e) Hypoxia

Q.7 in an Asthamtic female,immeditae treatment of HPTN during intra-operative HPTN, is
a) sublingual glycerine trinitate
b) intra.venous nitroglycerine
c) propranalol
d)

Q.8 During giving local anaestheia, the long needle goes far into greater palatine canal,causing anaesthesia of an autonomic ganglion,as a result along with dryness of nasal mucosa also occurs

a) decreased secretions of Parotid
b) decreased secretion of Submandibular & sublingual glands
c)

Q.9 Tissue which has in-ability to replace dead cells

a) Heart
b) Kidney
c) Liver
d) Bone
e) Bowl Mucosa

Q.10 Non-essential amino acid includes

a) Leucine
b) Iso-leucine
c) Methionine
d) Tyrosine

Q.11 Metabolic Alkalosis is caued by
a) Chronic Hypoventilation
b) Pancreatic Fistula
c) hyperglycemia
d) ATN

Q.12 Glucronide conjugation of drugs
a) causes inactivation of drug
b) is Type 1 reaction
c) makes drug insoluble in water
d) increases its effects

Q.13 A patient having generalized body weakness & numbness,
on investigation he is having Un-conjugated Bilirubinemia,
Hb= 7.4 md/dl MCV..> 120 fl,
the anemia is due to ....
a) Hemolysis
b) Vit B 9 def.
c) Vit B 12 def.
d) Hypersplenisim

Q.14 Tissue with Dual autonomic supply but not reciprocal suuply is
a) Skin
b) Blood vessels
c) Pupil
d) Salivary glands
e) Ciliary muscle

Q.15 Cause of joint pain in Deep sea divers
a) arterial embolism
b) venous embolism
c) DIC
d) thromboembolism

Q.16 In summer,in a fasting man the cause of concenterated urine is
a) Skin
b) Blood vessels
c) Pupil
d) Salivary glands
e) Ciliary muscle

Q.15 Cause of joint pain in Deep sea divers
a) arterial embolism
b) venous embolism
c) DIC
d) thromboembolism

Q.16 In summer,in a fasting man the cause of concenterated urine is
a) ADH
b) No Oral intake
c) Aldosterone
d) increased sweeting

Q.17 A 35 yr old man is having bilateral ptosis of eye during evening since last few weeks,the confirmatory test of the diagnosis will be
a) Tensilon Test
b) Ach Receptor Antibody Test
c) blood culture
d) CT scan Brain

Q.18 if a High Dextrose water is infusion given to a person,it inhibits
a) Cotisol
b) ADH
c) Aldosterone
d) Insulin

Q.19 Parasympthatic supply of Sigmoid Colon is
a) Sacral segments S2,S3,S4
b) Pelvic splanchnic Nerves
c) vagus nerve
d)

Q.20 which does not take part in inflamatory reactions
a) Adrenaline
b) Histamine
c) 5-hydroxy tryptamine
d) Dopamine

Q. 21 Parietal & Visceral Pericardium is supplied by
a) Phrenic Nerve
b) Sympthatic Nerves
c) Vagus neve
d) Cardiac Plexus

Q.22 A young man had sinjury to the neck with sum sharp object,3 yrs ago,
Now he notices a bulging swelling above the clavicle on sneezing & coughing,
this swelling most probably due to...
a) Injury to deep fascia of neck
b) demage to supra-pleural membrane
c) Un-united first Rib Fracture

Q.23 Middle meningeal artery if ruptured while meinges are intact,the Haemorrhage will be
a) Epidural
b) Subdural
c) Intracranial
d)

Q.24 Dorsal Rami of the cervical nerves innervates
a) Abductor Pollices
b) Extensors of Limbs
c) Extensors of Trunk
d) Stabilizers of Shoulder

Q.25 Muscles of Hand supplied by
a) ventral rami of C-8
b) Ventral branches of T-1
c) Median Nerve
d) Ulnar Nerve
e) Radial Nerve

Q.26 A person has sharp knife injury to upper medial aspect of arm,
after which He is unable to Flex his elbow & having loss of cutaneous sensations on lateral aspect of forearm,
the nerve injured is
a) Median Nerve
b) Axillary nerve
c) Radial Nerve
d) Musculocutaneous Nerve

Q. 27 A Transplant from identical twin is
a) Allograft
b) Heterograft
c) Homograft
d) Isograft
e) Xenograft

Q.28 Therapeutic Index of a drug indicates its
a) Effectivity
b) Efficacy
c) Potency
d) Toxicity

Q.29 Pharmakokinetic interaction among drugs is examplified by :
a) Shortening of action of Procaine by Adrenaline
b) increase peripheral toxicity of Levodopa with Carbidopa
c) increase toxicity of Methotrexate by Aspirin
d) prevention of Nitroglycerine induced tachycardia by Propranolol
e) blokade of acetylcholine receptors by atropine

Q.30 A 30 years old 75 kg Diabetic man with recent diagnosis of Hypertension,
On ECG : Left Ventricular Hypertrophy
s.Urea -- 20 mg/dl s.Creatinine -- 0.7 mg/dl
s.Uric Acid-- 7.5 mg/dl s.Na -- 140 mmol
s. K-- 2.5 mmol s.Cl --- 103 mmol
s.HCO3 -- 23 mg/dl 24 Hr Urinary Proteins-- 30
& Fasting BSL--- 80 mg/dl
The cause is.......
a) Essential HPTN
b) Diabetic Nephropathy
c) Pheochromocytoma
d) Addison Disease
e) Primary HyperAldosteronism

Q.31 Acute Tubular Necrosis is characterized by
a) Hyper-kalemia
b) Initially concenterated urine
c) Metabolic Alkalosis
d) s.Urea is increased & s.creatinine is normal

Q.32 GFR is measured by clearance of
a) Inulin
b) Creatinine
c) Urea
d) Glucose

Q.33 Sarcoidosis is diagnosed microscopically by
a) Granuloma with Asteroid
b) Non-caseating Granuloma
c) Caseating Granuloma
d) Macrophages & Giant cells

Q.34 Multipule sclerosis is characterized by...
a) Lewy Bodies in Neucleus
b) Ptachy demylination with white fiber gliosis
c) Axonal degeneration
d)

Q.35 What is INAPPROPRIATE about Vagus Nerve..
a) its longest Cranial Nerve
b) passes in between IJV & ICA
c) passes posterior to Carotid Sheath
d) Gives Recurrent Laryngeal Nerve
e) gives Superior Laryngeal Nerve

Q.36 Thymus is
a) Rich in Lymphocytes
b) Present at birth but shorly regree after birth
c) derived from 4th Pahryngeal Pouch
d) is a part of Thyroid
e) Lies posterior to Trachea

Q.37 True statement about Down Syndrom is
a) Trisomy 23
b) contains single X chromosome
c) more chances with increasing maternal age

Q.38 Kleinifilter syndrome
a) contains single X chromosome
b) less chances of Mental retardation
c) phenotypically female

Q.39 Following is Autosomal Dominant Disorder
a) Phenylketonuria
b) Hereditary Spherocytosis
c) Hemophilia A
d) Cystic Fibrosa

Q.40 At 35 weeks of Gestation,in sample taken from amniocentesis,
there is increased Alpha-Fetoprotein,its most probable cause is..
a) Down syndrome
b) Turner syndrome
c) Spina Cystica
d) Hydrocephalous
e)

Q.41 Thoracic Duct....
a) recieves Lymph from both right & left sides
b) lies in posterior mediastinum
c) passes just right to the thoracic aorta
d) extends from upper abdoment to neck
e) has a dilatation called Cisterna

Q.42 Rate of passage of food in esophagus depends upon
a) Gravitational Force
b) Neuromuscular excitation different @ upper & lower oesophagus
c) progressive peristalsis in esophagus
d) Acidity

Q.43 @ Leprotomy Retroperitoneal Abscess was found,the site woud be
a) Stomach
b) Sigmoid Colon
c) Transverse Colon
d) Ascending Colon
e) Small intestine

Q.44 Source of Estrogen & Progesterone in last trimester is
a) Chorionic Villus
b) Placenta
c) Overy
d) Adenohypophysis
e) Corpus Leuteum

Q.45 A patient having Facial deviation along with loss of sensations on anterior 2/3 rd of tongue,the leision lies in
a) Facial Canal
b) Internal auditary meatus
c) Facial Nerve Nucleus
d) Stylomastoid Foramen

Q.46 All are the branches of Vagus nerve EXCEPT
a) Auricular
b) Lacrimal
c)Pharyngeal
d) Recurrent Laryngeal

Q.47 Following nerve lies in the Cavernous Sinus
a) Opthalmic
b) Occulomotor
c) Abducent
d) Trigeminal

Q.48 In a Pituitary Adenoma,the Bitemporal Hemianopia occurs due to leison of
a) Central part of Optic chiasma
b) Optic Nerve
c) Optic Tract
d) peripheral Part of Optic chiasma
e) Lateral Geniculate body

Q.49 Muscle of Forced Expiration is
a) Internal Intercostal
b) External Intercostal
c) Sternoceidomastoid
d) Scalenus Anterior
e) Scalenus Medius

Q.50 Na Retension is associated with
a) Dehydration
b) increase ADH
c) Decreased Aldosterone
d) Heart Failure
e) Hyperthyroidism

Q.51 Von-Willebrand Disease is
a) Autosomal Dominant
b) Autosomal Recessive
c) in some family members asoociated with Factor IX deficiency
d) in some family members associated with normal Factor IX

Q.51 A male wd A+ (Ao,DD) Blood group, married to a female having
B+ (Bo,Dd ) blood group,children can have all blood gp EXCEPT
a) AB +ve
b) AB -ve
c) A + ve
d) B +ve
e) O -ve

Q.52 Vital Capacity
a) measured directly by Spirometry
b) is decreased in some Lung diseases
c) is the sum of Tidal Volume+ERV+IRV

Q.53 When a branch of Pulmonary Artery is blocked by embolus,following Lung function increases
a) Alveolar Co2
b) Alveolar O2
c) Pulmonary artery O2
d) Pulmonry artery Co2
e) Ventilation Perfusion

Q.54 Difference between Adenoma & Hyperplasia is
a) increase in size of cell
b) increase in No. of cells
c) Capsule
d)
Q.55 In a CLD patient presenting with Haematemesis,the preferred immediate treatment is
a) Octeriotide
b) Vit K
c) formed Platelet Conc.
d) PPI
e)whole blood
Q.56 Among most important initial steps in apoptosis
a) Activation of Bcl-2 Receptors
b) Activation of Caspases
c) Water influx into the cell
d)
Q.57 After a trauma, a person has inability to stand from sitting position,
the nerve demaged is
a) Infragluteal
b) Supragluteal
c) Schiatic
d) Femoral
e) Obturator

Q.58 About K - Regulation , following is correct
a) K is 98% in the cells
b) normally completely reabsorbed in Distal tubule
c) increase water affects K-balance
d) decrease in D.K

Q.59 A man with persistant fits without regaining consciousness for 30 minutes,
the immediate treatment is with
a) Carbamazepine
b) Valporate
c) Lorazepan
d) .......
Q.60 An unconsious man with pin-point pupils not responding to Naloxone,the probable cause is
a) Heroin
b) Hasheesh
c) Morphine
d) Phenobarbitone

Q.61 Stomach gets its arterial supply from all EXCEPT
a) Ceiliac artery
b) Splenic Artery
c) Superior Mesenteric Artery
d) Hepatic Artery

Q.62 The Hormone which stimulates release of HCO3 from Pancreas without stimulating pancreatic enzyme secretions,is
a) CCK
b) Secretin
c) Gastrin
d) Pepsin
e) Mucin

Q.63 Supra-Renal Gland arterial supply
a) recieves all braches directly from Aorta
b) recieves blood from 3 sources
c) recieves branches from both renal arteries
d) recieves blood from inferior phrenic artery

Q.64 Stenson's duct
a) arises from posterior surface of Parotid
b) pierces the Buccinator muscle
c) opens in the oral cavity against ....

Q.65 Which infection is not caused by DNA virus
a) Chicken Pox
b) Herpes Simplex
c) Herpes Zoster
d) Mumps
e) Small Pox

Q.66 On examination of a female,a plaque like leision seen on Postero-superior aspect of Vagina,it is
a) Squamous Cell CA
b) Adenocarcinoma
c) Rhabdomyosarcoma
d) wart

Q.67 About CSF most appropriate statement is
a) it is ultrafilterate of Plasma
b) has more glucose than blood
c) has cushioing effect
d) absorbed in Choroid Plexus

Q.68 On standing from a sitting position,@ apex of lung there is increase in
a) Blood Flow
b) Ventilation
c) pO2
d) pCO2

Q.69 Metastatic Calcification occurs mostly in
a) Kidney
b) Bone
c) Lung
d) Intestine
e) Pancreas

Q.70 Basal Cell Carcinoma involves
a) Buccal Mucosa
b) Hard Palate
c) Soft Palate
d) Lower Lip
e) Oral Cavity

Q.71 A female underwent Gastrectomy for Zollinger-Ellison Syndrome,given Parenteral Vit B-12,
the inability to absorb B-12 is due to loss of...
a) Parietal Cells
b) Gastric Cells
c) Cardiac Ceells

Thursday, October 18, 2007

Welcome friends!

Assalam o Allaikum everybody.

Now that the july 23 exam date is just around the corner I wish you all success and good luck! May we all shine and rise in all our endeavours.

May I request you all who have benefited from this website in any way to kindly post your own recalled questions soon after the October exam (all specialities). Out of experience, I can say that after the 1st few days of exam, one is not able to jog the memory and reproduce much. So, kindly do make sure to send your recalled stems/q's so future candidates could benefit from them.

Please leave comments at the end of the posts or at the extreme end of this page regarding feedback and suggestions.

And send your recalled stuff to medguru88@gmail.com

Jazakallah.

p.s. Do remember me in your prayers as I am writing the oct exam aswell.